Distinct impacts of syndesmophyte formation on male and female patients with ankylosing spondylitis

International Journal of Rheumatic Diseases, 04/19/2012

Ankylosing spondylitis (AS) patients with syndesmophytes experienced imbalance of bone metabolism due to inflammatory cytokine release. Male AS patients had high levels of bone resorption markers, cytokines and adhesion molecules, reflecting a disorder of bone metabolism.

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