Orthopedics Medical News about Arthroscopy Inflammation Ketorolac Knee Morphine Synovial Membrane

Your Unread Messages

See All

Hello, Mary O'connor
Manage E-mail | Logout

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Rapid correction of low vitamin D status in nursing home residents

3. 2008 Exclusive Survey—Earnings: Good news for primary care income

4. Medicare pay-for-reporting effort draws fire from frustrated doctors

5. Debunking Myths in the US Healthcare System

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Ketorolac But Not Morphine Exerts Inflammatory and Metabolic Effects in Synovial Membrane After Knee Arthroscopy: A Double-Blind Randomized Prospective Study Using the Microdialysis Technique
Regional Anesthesia and Pain Medicine, 11/04/09

Stalman A et al. – To the authors' knowledge, this is the first study on the local metabolic and inflammatory effect of intra–articularly administered morphine or ketorolac. For the first time, glutamate was studied in synovial tissue, and our results suggest that local release of glutamate may be important for nociception and inflammation. The effects of ketorolac on PGE2 implicates a local effect on inflammation and possibly, also nociception, but it should be remembered that 60 mg of ketorolac given intra–articularly also has a systemic effect. Release of glycerol after administration of ketorolac may indicate a toxicity of nonsteroidal anti–inflammatory drugs that must be further evaluated.

<< Previous
Incidence of Groin Pain After Metal-on-Metal Hip Resurfacing

Next >>
Femoral neck fracture after removal of PFNA-blade—Case report and...

Estrone/17[beta]-estradiol conversion to, and tumor necrosis factor inhibition by, estrogen metabolites in synovial cells of patients with rheumatoid arthritis and patients with osteoarthritis
Arthritis & Rheumatism, 10/01/09 Relevance Score: 80%

Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation
Arthritis & Rheumatism, 11/03/09 Relevance Score: 79%

MR Imaging of Synovial Disorders of the Knee
Seminars in Musculoskeletal Radiology, 11/06/09 Relevance Score: 69%

Spinal mepivacaine with fentanyl for outpatient knee arthroscopy surgery: a randomized controlled trial
Canadian Journal of Anesthesia, 10/29/09 Relevance Score: 69%

Monocyte derived interleukin (IL)-23 is an important determinant of synovial Il-17A expression in rheumatoid arthritis
Journal of Rheumatology, 10/05/09 Relevance Score: 68%