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Thromboprophylaxis in Patients with Acute Spinal Injuries: An Evidence-Based Analysis
Journal of Bone and Joint Surgery, 11/03/09

Ploumis A et al. – The prevalence of deep–vein thrombosis following a spine injury is higher among patients who have a spinal cord injury than among those who do not have a spinal cord injury. Therefore, thromboprophylaxis in these patients should start as early as possible once it is deemed safe in terms of potential bleeding complications. Within this population, low–molecular–weight heparin is more effective for the prevention of deep–vein thrombosis, with fewer bleeding complications, than unfractionated heparin is. The use of vitamin K antagonists appeared to be effective for the prevention of pulmonary embolism.

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