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PTH and IL21R May Underlie Variation of Femoral Neck Bone Mineral Density as Revealed by a Genome-Wide Association Study
Journal of Bone and Mineral Research, 11/03/09
Guo Y et al. – The effect size of each SNP was ~0.11 SD estimated in the discovery sample. PTH and IL21R both have potential biological functions important to bone metabolism. Overall, the findings provide some new clues to the understanding of the genetic architecture of osteoporosis.
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