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Does standardized BMD still remove differences between Hologic and GE-Lunar state-of-the-art DXA systems?
Osteoporosis International, 10/30/09

Fan B et al. – The sBMD values were shown to be equivalent within 1.0% for hip but were significantly different for spine on the two systems. Biases may persist in pooled sBMD data from different manufacturers.

• Spine and bilateral femurs of 87 postmenopausal women scanned on both Hologic Delphi and GE-Lunar Prodigy DXA systems at 3 different clinical centers
• BMD results converted to sBMD using equations previously developed
• Linear regression analysis used to describe relationship of 2 systems’ BMD results
• Bland–Altman analysis used to assess differences in measures

• Apex and Prodigy sBMD values highly correlated
• Spine L1-L4 and L2-L4 sBMD values had significant intercepts and slopes for Bland–Altman regression, with mean differences of 0.042 g/cm2 (4.1%) and 0.035 g/cm2 (3.2%), respectively
• Total hip and neck sBMD showed no significant intercept and slope, except left total sBMD had a significant difference between 2 systems of 0.009 g/cm2

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