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The effect of weight training on bone mineral density and bone turnover in postmenopausal breast cancer survivors with bone loss: a 24-month randomized controlled trial
Osteoporosis International, 10/06/09

Waltman NL et al. – Strength/weight training exercises may prevent loss of BMD in postmenopausal BCS at risk for bone loss.

• Postmenopausal BCS (223) randomly assigned to exercise plus medication or medication only groups
• Both groups received 24 mos of 1,200 mg of calcium and 400 IU of vitamin D daily and 35 mg of risedronate weekly
• Exercise group additionally had ST exercises twice weekly

• After 24 months, women who took medications without exercising had significant improvements in BMD at total hip and spine and significant decreases in Alkphase B and serum NTx
• Women who also exercised had additional increases in BMD at femoral neck , total hip , spine , total radius , and additional decreases in Alkphase B and Serum NTx
• Additional changes in BMD and bone turnover with exercise not significant
• Subjects who were ≥ 50% adherent to exercise were less likely to lose BMD at the total hip and femoral neck

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