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The Risk of Fractures Associated with Thiazolidinediones: A Self-controlled Case-Series Study
PLoS Medicine, 09/30/09
Douglas IJ et al. – Within individuals who experience a fracture, fracture risk is increased during periods of exposure to thiazolidinediones (both rosiglitazone and pioglitazone) compared with unexposed periods. The increased risk is observed in both men and women and at a range of fracture sites. The risk also increases with longer duration of use.
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