Orthopedics Medical News about Arthritis, Rheumatoid

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Biological targets in the treatment of rheumatoid arthritis: a comprehensive review of current and in-development biological disease modifying anti-rheumatic drugs
Biologics: targets & therapy, 09/28/09

Kukar M et al. – The current and upcoming biological agents are primarily aimed at neutralizing circulating and cell–bound pro–inflammatory cytokines, interfering in the interaction of antigen–presenting and T–lymphocytes, eliminating circulating B–lymphocytes or by interfering with the intracellular signaling mechanisms of immuno–competent cells that lead to inflammation. These agents have improved the currently available treatments due to greater efficacy, fast action and greater tolerability.

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