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The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro
Bone , 09/09/09
Mitrofan LM et al. – The current data suggest that ZOL–induced IPP/ApppI formation can contribute to ZOL–induced apoptosis. This mechanism and the inhibition of protein prenylation, both outcomes of FPPS inhibition in mevalonate pathway, seem to act in concert in ZOL–induced apoptosis in cancer cells.
Today in Bone Metabolism...keeping you current
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Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/09/09
Bisphosphonate therapy: When not to monitor BMD
The Journal of Family Practice, 11/02/09
Effect of Rosiglitazone, Metformin, and Glyburide on Bone Biomarkers in Patients with Type 2 Diabetes
Journal of Clinical Endocrinology and Metabolism, 11/10/09
Today in Oncology...keeping you current
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A phase 2 trial exploring the effects of high-dose (10,000 IU/day) Vitamin D3 in breast cancer patients with bone metastases
Cancer, 11/25/09
Endoprosthetic proximal femur replacement: Metastatic versus primary tumors
Surgical Oncology, 11/05/09
Survival in high-grade osteosarcoma: improvement over 21 years at a single institution
Annals of Oncology, 11/16/09
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