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Systemic effects of zoledronic acid in children with traumatic femoral head avascular necrosis and Legg–Calve–Perthes disease
Bone , 08/11/09
Johannesen J et al. – The authors here report that ZA in otherwise healthy children with femoral head AVN increases BMD – most pronounced in the LCPD group – and reduces bone modeling and turnover. Further efficacy and safety data are required before this therapy can be widely recommended.
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