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The effects of long-term raloxifene and estradiol treatments on bone in a patient with congenital aromatase deficiency
Bone , 08/06/09
Zirilli L et al. – This study shows that the management of aromatase deficiency in the male cannot consider raloxifene as a first choice treatment, but should be still based on estrogen replacement treatment since in this patient the completion of bone maturation has only been obtained once estradiol substitution was performed. The present case also demonstrates that raloxifene is able to improve BMD in aromatase–deficient men.
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Today in Clinical Pharmacology...keeping you current
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