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See Latest ArticlesBetter Prophylaxis Against Surgical Site Infection with Local as Well as Systemic Antibiotics
Journal of Bone and Joint Surgery, 08/19/09
Cavanaugh DL et al. – The combination of systemic cefazolin and local gentamicin proved to be the most effective regimen. Local injection of gentamicin proved more effective than systemic administration of cefazolin but was not as effective as the combination of both antibiotics. The initially high concentrations of locally applied antibiotic and the utilization of two different classes of antibiotics may have contributed to the observed efficacy.
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