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See Latest ArticlesIncreasing the Osmolarity of Joint Irrigation Solutions May Avoid Injury to Cartilage: A Pilot Study
Clinical Orthopedics and Related Research, 08/21/09
Amin AK et al. – Increasing the osmolarity of 0.9% saline and Hartmann’s solution to 600 mOsm decreased in situ chondrocyte death in the superficial zone of injured cartilage. Compared with 0.9% saline, Hartmann’s solution was associated with greater chondrocyte death in the superficial zone of injured cartilage, but not when the osmolarity of both solutions was increased to 600 mOsm. These experiments may have implications for the design of irrigation solutions used during arthroscopic and open articular surgery.
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