Orthopedics Articles

Orthopedics

sponsor
Become a Member Today!
Register
Email:


Password:

Remember me
Forgot your Password?
Invite Code?
Article ID

Your Article Summary

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Chappell AS et al. – Herein, the authors report the results of a 13–week, randomized, double–blind, placebo–controlled trial of duloxetine (60–120mg/day) versus placebo in the treatment of knee pain in 231 patients meeting clinical and radiographic criteria for osteoarthritis of the knee. Duloxetine was superior to placebo on the primary efficacy measure (weekly mean 24–h pain scores) beginning at Week 1 and continuing through the treatment period. There was also a significant improvement in the WOMAC physical functioning subscale and several other secondary outcomes. Adverse–event rates did not differ significantly between treatment groups (49.5% for duloxetine 60–120 mg/day, and 40.8% for placebo).


Related Articles

Correlates of Pain Intensity in Men and Women With Hip and Knee Osteoarthritis. Results of a National Survey: The French ARTHRIX Study
The Clinical Journal of Pain, 10/23/09    Relevance Score: 83%

Medical decision making in patients with knee pain, meniscal tear, and osteoarthritis
Arthritis Care and Research, 11/04/09    Relevance Score: 82%

Acupuncture for pain and osteoarthritis of the knee: a pilot study for an open parallel-arm randomised controlled trial
BMC Musculoskeletal Disorders, 10/26/09    Relevance Score: 82%

Viscosupplementation Treatment of Arthritis Pain
Current Pain and Headache Reports, 11/06/09    Relevance Score: 81%

Health-related quality of life (Nottingham Health Profile) in knee osteoarthritis: Correlation with clinical variables and self-reported disability
Rheumatology International, 10/22/09    Relevance Score: 81%

Today in Clinical Pharmacology...keeping you current

A walking model to assess the onset of analgesia in osteoarthritis knee pain
Osteoarthritis and Cartilage , 03/19/10

A review of the effect of anticonvulsant medications on bone mineral density and fracture risk
The American Journal of Geriatric Pharmacotherapy, 03/19/10

Severe exfoliative dermatitis caused by strontium ranelate: two cases of a new drug reaction
Age and Aging, 03/19/10


Sponsor

Article Search

Keyword:

Search:

Published within

Sort By:
Date
Relevance


Sponsor

Sponsor

Send this Summary to a Colleague

Enter email address