Orthopedics Medical News about pharyngeal arches

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Syndromes of the first and second pharyngeal arches: A review
American Journal of Medical Genetics, 07/22/09

Passos–Bueno MR et al. – Based on the molecular analysis of balanced translocation in an OAVS patient, it has been suggested that abnormal expression of BAPX1 possibly due to epigenetic disregulation might be involved with the etiology of OAVS. Involvement of environmental events has also been linked to the causation of OAVS. Identification of factors leading to these disorders are important for a comprehensive delineation of the molecular pathways underlying the craniofacial development from the first and the second pharyngeal arches, for genetic counseling and to open alternative strategies for patient treatment.

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