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Analgesic Prescribing for Musculoskeletal Complaints in the Ambulatory Care Setting After the Introduction and Withdrawal of Cyclooxygenase-2 Inhibitors
Archives of Physical Medicine and Rehabilitation, 07/16/09
Wilson RD - COX-2 inhibitors may have been prescribed as substitutes for nsNSAIDs initially, but nsNSAID prescriptions returned to prior levels by 2005 as COX-2 inhibitor prescriptions declined. An increase in nonnarcotic analgesic prescribing in 2005 may have been caused by a class effect concern for NSAIDs. Prescribing of opiate analgesics and adjuvant analgesics increased over the study period, although apparently not in substitution for NSAIDs.
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