Orthopedics Medical News about Coticosteroids, bone density, bone strength

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The effects of corticosteroids on bone growth and bone density
Annals of Allergy, Asthma, and Immunology, 07/06/09

Weldon D – Study suggests that preventing corticosteroid-induced effects on bone metabolism can allow effective treatment of allergic disease without long-term adverse effects.

Methods

Main objectives of this study were to define the effects of both parenteral and inhaled corticosteroids on:
- Bone growth in children and
- Development of osteopenia and osteoporosis in children and adults
Articles in PubMed and MEDLINE published from 1983 to 2008 were searched
Keywords: corticosteroids and bone growth, osteopenia, osteoporosis, and bisphosphonates
Publications reviewed include randomized, placebo-controlled studies of both children and adults

Results

Because systemic and high-dose inhaled corticosteroids affect bone growth of children taking these medications, stadiometry should be used to measure the growth of children
Osteoporosis due to repetitive courses of oral or parenteral corticosteroids and inhaled corticosteroids can develop gradually in aging adult
Prophylaxis against osteoporosis requires:
- An index of suspicion
- Assessment of bone density
- Supplemental calcium and vit D, and
- Use of bisphosphonates
  to prevent bone fractures that could compromise the pt's quality of life

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