Orthopedics Medical News about low back and neck pain; cyclobenzaprine ER

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Cyclobenzaprine ER for muscle spasm associated with low back and neck pain: two randomized, double-blind, placebo-controlled studies of identical design
Current Medical Research and Opinion, 06/17/09

Malanga GA et al. - Once-daily CER 15mg (study 2) and CER 30mg (study 1) were effective in treating muscle spasm associated with painful musculoskeletal conditions after 4 days of treatment. Differences between CER and placebo groups did not reach statistical significance on all efficacy measures, and the protocols were not powered to detect differences between active treatment arms. CER was generally safe and well tolerated, with low rates of somnolence.

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