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Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study
Current Medical Research and Opinion, 06/17/09
Hale M et al. - Tapentadol is a novel, centrally acting analgesic with two mechanisms of action, ?-opioid receptor agonism and norepinephrine reuptake inhibition, in a single molecule. This phase III, randomized, double-blind, active-controlled study evaluated the tolerability of tapentadol immediate release (IR) and oxycodone IR for low back pain or osteoarthritis pain (hip or knee), using flexible dosing over 90 days...During this 90-day study, tapentadol IR was associated with improved gastrointestinal tolerability compared with oxycodone IR while providing similar pain relief.
Today in Clinical Pharmacology...keeping you current
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Bisphosphonate therapy: When not to monitor BMD
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Today in Hip...keeping you current
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Doxycycline for osteoarthritis of the knee or hip
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S-Adenosylmethionine for osteoarthritis of the knee or hip
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Knee and Hip Radiographic Osteoarthritis Predict Total Hip Bone Loss in Older Adults: A Prospective Study
Journal of Bone and Mineral Research, 10/16/09
Today in Knee...keeping you current
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Doxycycline for osteoarthritis of the knee or hip
Cochrane Reviews, 10/23/09
S-Adenosylmethionine for osteoarthritis of the knee or hip
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Medical decision making in patients with knee pain, meniscal tear, and osteoarthritis
Arthritis Care and Research , 11/04/09
Today in Spine...keeping you current
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Cervical Radicular Pain
Pain Practice, 10/07/09
Opioid Use for Chronic Low Back Pain: A Prospective, Population-based Study Among Injured Workers in Washington State, 2002-2005
The Clinical Journal of Pain, 10/20/09
Causes and prevention of low back pain in young athletes
Paediatrics & Child Health, 10/19/09
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