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Variation in Chondroadherin Abundance and Fragmentation in the Human Scoliotic Disc
Spine, 06/16/09
Haglund L et al. - As CHAD can interact with both the ECM and the cells, it can provide a mechanism for regulating cell metabolism and ECM structure, and so play a role in promoting matrix homeostasis. Thus, changes in CHAD abundance or structure could be associated with the pathologic changes occurring in the scoliotic IVD.
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