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Kim HKW et al. - Acute ischemic injury to the immature femoral head induced severe hypoxia and cell death in the bony epiphysis and the deep layer of the epiphyseal cartilage. Viable chondrocytes in the superficial layer of the epiphyseal cartilage showed HIF-1(alpha) activation and VEGF upregulation with subsequent revascularization occurring in the cartilage.


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