Orthopedics Medical News about low bone mineral density;femoral neck;predictor of increased mortality

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Low bone mineral density at femoral neck is a predictor of increased mortality in elderly Japanese women
Osteoporosis International, 06/09/09

Suzuki T et al. - Findings suggest that preventive strategies should be considered to increase and maintain high bone mineral density (BMD) at the femoral neck in elderly subjects not only to prevent osteoporosis and its associated fractures but also probably to reduce mortality risk.

Methods

Aim was to determine whether low BMD at the femoral neck independently predicts all-cause mortality in elderly Japanese community-dwelling women (n=271; age: 67-89 yrs)
Cox proportional hazard model was used to examine these associations

Results

During a 12-yr f/u period, 81/271 women (29.9%) died
An independent relationship was found between baseline BMD at the femoral neck and mortality risk
Mortality risk was increased by:
- 2.80-fold in subjects with osteoporosis or
- 2.94-fold in subjects in the lowest tertile or
- 3.61-fold in subjects in the lowest quartile of BMD
After adjusting for major potential confounding factors for mortality, subjects with osteoporosis in the lowest tertile or in the lowest quartile had a significantly increased risk of mortality
BMD measurement at the trochanter showed similar but weaker results

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