Orthopedics Medical News about osteoporosis medications;improve adherence;interventions

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Interventions to improve adherence and persistence with osteoporosis medications: A systematic literature review
Osteoporosis International, 06/12/09

Gleeson T et al. – Study demonstrates that few interventions to improve adherence and persistence with osteoporosis medications were efficacious, however no clear trends were identified.

Methods

Aim was to examine the design and efficacy of published interventions to improve adherence and persistence of osteoporosis medication
Search of medical literature databases published between Jan 1990 and July 2008
Papers that described interventions and provided results for control and intervention subjects were selected
Design and methods of each study were assessed

Results

7 studies met eligibility requirements; 5 of 7 studies provided adherence data
Of those 5 studies, 3 showed a significant improvement in adherence by the intervention group, with effect sizes from 0.17 to 0.58
5 of the 7 studies provided persistence data
Of those 5, one reported improvement in persistence by the intervention group, with an effect size of 0.36

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