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The Synergistic Effect of Autograft and BMP-7 in the Treatment of Atrophic Nonunions
Clinical Orthopedics and Related Research, 04/28/09
Giannoudis PV et al. - Combining autologous bone graft and recombinant human bone morphogenetic protein-7 to treat long-bone fracture aseptic atrophic nonunions theoretically could promote bone healing at higher rates than each of these grafting agents separately. The authors retrospectively reviewed prospectively collected data on patient general characteristics, clinical outcomes, and complications over 3 years to determine the healing rates and the incidence of complications and adverse events of this “graft expansion rationale.”
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