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Perfusion and cyclic compression of mesenchymal cell-loaded and clinically applicable osteochondral grafts
Knee Surgery, Sports Traumatology, Arthroscopy, 04/15/09
Haasper C et al. - Perfusion induced collagen II and cyclic compression increased collagen X expression. Matrix stiffness was significantly increased after 28 days of cyclic compression. Cyclic compression of cell-loaded hybrid constructs enhanced chondrocyte differentiation and matrix stiffness. This system is a promising tool with a view to a later clinical application.
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