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Could insertion of the particles that induce osteolysis be a new treatment option in heterotopic ossification
Medical Hypotheses, 04/21/09
Yuan P et al. - Nowadays, periprosthetic osteolysis induced by wear debris is the most widely accepted cause of aseptic loosening after total joint replacement. A large number of researches have identified metal particles can stimulate bone resorption by targeting osteoclasts. So it is hypothesized that the insertion of metal particles in the region surrounding heterotopic bone could be a new treatment option in HO.
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