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See Latest ArticlesEvolving gene therapy approaches for osteosarcoma using viral vectors: Review
Bone , 03/21/07
M.A. Witlox, et al. - We recognize that several other issues have arisen which hamper progress in the field of cancer gene therapy. We, therefore, review viral-induced toxicity in the host and vector delivery issues which have been found to potentially influence safety. We end with a brief perspective including commenting on animal models used in examining delivery strategies for osteosarcoma gene therapy. The challenges remaining are touched upon most especially the need to deal with pulmonary metastatic disease from OS
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