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See Latest ArticlesDiscontinuation of Antiresorptive Therapies: A Comparison between 1998–2001 and 2002–2004 among Osteoporotic Women
Journal of Clinical Endocrinology and Metabolism, 03/12/07
Julie Blouin, et al. – What are the significant determinants of ART discontinuation?
>Summary: Two cohorts of women aged 70 or older were profiled using Régie de l’Assurance Maladie du Québec databases. Discontinuation was defined as a lapse of 30 d or longer after completion of a refill. Switching from one ART to another was allowed. Probability of discontinuation was estimated using Kaplan-Meier analysis. Multivariate Cox models were used to identify potential determinants of ART discontinuation over 1 yr.
Outcomes: Significant determinants of ART discontinuation within 1 yr included bone mineral density testing performed within 2 yr prior to initiation of therapy and having consulted more than two pharmacies in the year before starting therapy. Even if new dosing regimens were introduced, discontinuation of ART among osteoporotic women remains high
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