Prospective study of fetal DNA in serum and disease activity during pregnancy in women with inflammatory arthritis Zhen Yan, et al. - Rheumatoid arthritis (RA) usually improves during pregnancy and recurs postpartum. Fetal cells and cell-free DNA reach the maternal circulation during normal pregnancy...Conclusion: Changes in serum fetal DNA levels correlated with arthritis improvement during pregnancy and recurrence postpartum. Immunologic mechanisms by which pregnancy might modulate RA activity are described [more...]