Postoperative Culture Positive Surgical Site Infections After the Use of Irradiated Allograft, Nonirradiated Allograft, or Autograft for Spinal Fusion
Spine, 10/26/2009
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Mikhael MM et al. – There is no significant difference in the rate of infection following spine fusion using irradiated allograft, nonirradiated allograft, or autograft. The selection of bone graft
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Hyperuricemia Is a Mediator of Endothelial Dysfunction and Inflammation in Renal Allograft Recipients
Transplantation Proceedings, 10/30/2009
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Karbowska A et al. – Hyperuricemia is common in renal transplant recipients treated with calcineurin inhibitors. Uric acid induces glomerular hypertension, microvascular disease, and renal ... which uric acid injures renal allografts and the cardiovascular system remain unclear. Hyperuricemia mediates endothelial dysfunction and inflammation and via this pathway, possibly contributes to chronic allograft injury and cardiovascular events in renal allograft recipients.
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Results of 32 Allograft-prosthesis Composite Reconstructions of the Proximal Femur
Clinical Orthopedics and Related Research, 10/26/2009
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Biau DJ et al. – Allografts sterilized by gamma radiation showed worse resorption than fresh–frozen allografts. Based on reported results, allograft–composite prostheses do not appear to improve
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Hyperuricemia Is a Mediator of Endothelial Dysfunction and Inflammation in Renal Allograft Recipients
Transplantation Proceedings, 11/02/2009
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Karbowska A et al. – Hyperuricemia is common in renal transplant recipients treated with calcineurin inhibitors. Uric acid induces glomerular hypertension, microvascular disease, and renal ... which uric acid injures renal allografts and the cardiovascular system remain unclear. Hyperuricemia mediates endothelial dysfunction and inflammation and via this pathway, possibly contributes to chronic allograft injury and cardiovascular events in renal allograft recipients.
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Monocytes/macrophages in renal allograft rejection
Transplantation Reviews, 10/01/2009
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Magil AB – The recent demonstration that peritubular capillary deposition of complement split factor C4d, a marker for antibody–mediated rejection, is associated with relatively marked MO infiltration of the allograft during acute rejection is a ... development in our understanding of the role of the MO in rejection. High levels of MO in rejecting allografts have been associated with severe rejection, and glomerular MO infiltration in particular has been shown to be an indicator of poor graft outcome.
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Transplant Nephrectomy Associates with Improved Survival in Patients with Failed Renal Allograft
Journal of the American Society of Nephrology, 11/03/2009
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Ayus JC et al. – Within a large, nationally representative sample of high–risk patients returning to long–term dialysis after failed kidney transplant, receipt of allograft nephrectomy independently associated with ... technique
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Re-Do Aortic Root Replacement After an Allograft Aortic Root Replacement
Annals of Thoracic Surgery, 10/13/2009
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Vrtik M et al. – Structural degeneration of allograft aortic root is a global process. In addition to valvular degeneration, the allograft wall calcification poses a risk of systemic calcific embolization and late phase
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Genetic Polymorphisms of Immunoregulatory Proteins in Acute Renal Allograft Rejection
Transplantation Proceedings, 11/10/2009
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Krichen H et al. – The authors examined the relationship between CTLA–4 and CD28 gene polymorphisms and renal transplant outcomes. The study suggested that these alleles may confer protection against renal allograft loss.
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Incidence and predictors of osteonecrosis among cyclosporin- or tacrolimus-treated renal allograft recipients
Rheumatology International, 11/04/2009
Takao M et al. – There was a lower incidence of osteonecrosis of the hip and knee in renal allograft recipients treated with cyclosporin or tacrolimus. In the patients treated with improved ... osteonecrosis. Methods- The subjects were 232 renal allograft recipients who had MRI for osteonecrosis of the hip and knee 3 months or longer after transplant
Results- Evidence of osteonecrosis was visible on the MRI of 11 recipients (4.7%, 95
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Left versus right deceased donor renal allograft outcome
Transplant International, 11/06/2009
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Phelan PJ et al. – There were 47 death–censored allograft failures in the left–sided group compared to 57 in the right–sided group (P = 0.24). These observations show no difference in renal transplant outcome between ... ndash;sided deceased donor kidneys.
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