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Autocrine Vascular Endothelial Growth Factor Enhances Survival of Retinal Pigment Epithelium Cells under Oxidative Stress via the VEGF R-2/PI3K/Akt
Investigative Ophthalmology and Visual Science, 11/05/09

Byeon SH et al. – Autocrine VEGF–A enhanced RPE cell survival under oxidative stress; the autocrine VEGF–A/VEGF R2/PI3K/Akt pathway is involved. Neutralization of VEGF–A signaling, as in age–related macular degeneration eyes, may influence RPE cell survival.

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