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Gupta G et al. – There was a fading macular rash on the palms of his hands and the soles of his feet. The differential diagnosis for this combination of long–standing vitritis and retinal arteritis in the setting of multiple comorbidities suggestive of human immunodeficiency virus (HIV) is highly suspicious for syphilis, although it also includes necrotizing herpetic retinopathies, toxoplasmosis retinochoroiditis and non–infectious etiologies such as sarcoidosis. Serological testing confirmed the clinical diagnosis of tertiary syphilis and HIV. The eye pain and vitritis responded to intravenous penicillin G, however the vision remained unchanged.

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