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For moderate glaucoma cases that require more pressure–lowering results than milder cases, an additional surgical option is also available, but not in the United States. The iStent trabecular micro–bypass implant, in U.S. trials for FDA approval, offers potential benefits similar to those of viscocanalostomy. It lowers IOP without the formation of a filtering bleb and, therefore, without affecting the conjunctiva. It is delivered ab interno through a clear corneal incision, advanced through the trabecular meshwork and implanted through a pre–loaded applicator into Schlemm's canal.

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