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Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism
Molecular Vision, 09/25/09
Daugherty CL et al. – This preliminary results indicate that the arginine variant of rs1042522 within p53 is associated with increased risk of POAG. This variant has increased apoptotic potential, thus the retinal ganglion cells in carriers of the arginine allele may have greater susceptibility to apoptosis.
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