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Synthesis of sphingosine is required for oxidative stress-induced apoptosis of photoreceptors
Investigative Ophthalmology and Visual Science, 10/15/09

Abrahan C et al. – These results suggest that oxidative stress enhances formation of ceramide and its subsequent breakdown to Sph; ceramide and/or Sph would then trigger photoreceptor apoptosis. Preventing Sph synthesis or promoting its phosphorylation to S1P rescued photoreceptors, suggesting that Sph is a mediator of their apoptosis and modulation of Sph metabolism might be crucial for promoting photoreceptor survival.

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Sectoral thinning of the retina after branch retinal artery occlusion
Japanese Journal of Ophthalmology, 11/10/09 Relevance Score: 91%

Oxygen supply and consumption in the retina: implications for studies of retinopathy of prematurity
Documenta Ophthalmologica, 10/20/09 Relevance Score: 90%

The effect of contour line position on optic nerve head analysis by Heidelberg Retina Tomograph
European Journal of Ophthalmology, 11/09/09 Relevance Score: 87%

Combined Three-Dimensional Spectral OCT/SLO Topography and Microperimetry: Steps toward Achieving Functional Spectral OCT/SLO
Ophthalmic Research, 10/16/09 Relevance Score: 87%

Unintentional Displacement of the Retina after Standard Vitrectomy for Rhegmatogenous Retinal Detachment
Ophthalmology, 11/09/09 Relevance Score: 85%