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See Latest ArticlesCXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis
Experimental Eye Research, 09/11/09
Zhang Z et al. – These data suggest that CXCR4 but not CXCR7 plays a critical role in antigen–induced ocular inflammation by facilitating leukocyte infiltration. This study not only enhances the knowledge of the immunopathological mechanism of uveitis but also provides a novel rationale to target CXCR4 as an anti–inflammatory strategy to treat uveitis.
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