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Hemoglobin Expression and Regulation in Glaucoma: Insights into Retinal Ganglion Cell Oxygenation
Investigative Ophthalmology and Visual Science, 09/17/09
Tezel G et al. – Findings of this study provide new insights into tissue oxygen transport in the inner retina and optic nerve head through the regulated expression of Hb in macroglia and RGCs. Up–regulation of Hb expression appears to be an intrinsic protective mechanism to facilitate cellular oxygenation and may also provide free radical scavenging.
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