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High-resolution analysis of DNA copy number alterations in patients with primary open-angle glaucoma
Molecular Vision, 08/19/09
Abu–Amero KK et al. – Chromosomal deletions and/or duplications were not detected in POAG patients as compared to controls. Other chromosomal imbalances such as translocations, inversions, and some ploidies cannot be detected by current array comparative genomic hybridization technology, and other nuclear genetic, mitochondrial abnormalities, or epigenetic factors cannot be excluded as a possible contributing factor to POAG pathogenesis.
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