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Cost-effectiveness of ranibizumab compared with pegaptanib in neovascular age-related macular degeneration
Graefe's Archive for Clinical and Experimental Ophthalmology, 08/17/09
Hernandez–Pastor LJ et al. – The cost per QALY gained with monthly ranibizumab compared with pegaptanib in the minimally classic/occult neovascular AMD population is just below the €30,000 threshold below which new drugs are sometimes regarded as cost–effective strategies in Spain. In this model, the key variables with greater impact on the cost–effectiveness results were the selected time horizon and the chosen extrapolation method, the source for data on pegaptanib efficacy and the number of ranibizumab injections. When administered on an as–needed basis, ranibizumab was a cost–effective strategy compared to pegaptanib in this population.
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