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Featured distribution of AMD-susceptibility SNPs between ethnicities and the modifying effect of SNPs on AMD therapy
Expert Review of Ophthalmology, 08/12/09
Guan H et al. – The most global AMD alleles across ethnic groups are SNPs at the complement factor H and PLEKHA1/LOC387715/HtrA1. Individuals carrying AMD allele might have an altered response to current available therapies. Alleles that alter the AMD therapy effects are not necessarily AMD–susceptibility SNPs.
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