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Aberrant Wound-Healing Response in Mitomycin C-Treated Leaking Blebs
Archives of Ophthalmology, 08/13/09
Elner VM et al. – A desirable filtration bleb requires a sufficient reparative fibrovascular response to maintain an epithelial–stromal barrier to prevent leakage. Fibroblasts must lay down a continuous collagen–rich fibrous layer, rather than merely myxoid stroma, beneath the conjunctival epithelium to promote bleb stability. Surgical techniques and postsurgical care should aim to attain this desired outcome.
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