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Massive spontaneous choroidal hemorrhage in a patient with chronic renal failure and coronary artery disease treated with Plavix
European Journal of Ophthalmology, 08/25/09

Marco RD et al. – Massive spontaneous choroidal hemorrhage is an extremely rare event that usually has been described in older patients receiving anticoagulants or thrombolytic agents. Systemic hypertension, generalized atherosclerosis, and age–related macular degeneration are additional risk factors. In the present case, massive choroidal hemorrhage was associated with use of clopidogrel bisulfate in a patient with chronic renal failure. This report indicates that Plavix should be administered with caution in patients with chronic renal failure owing to the risk of serious choroidal bleeding.

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