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Dose–response relationship of inhaled corticosteroids and cataracts: A systematic review and meta-analysis
Respirology, 08/11/09

Weatherall M et al. – The risk of cataracts was increased by approximately 25% for each 1000 mug per day increase in the dose of beclomethasone dipropionate or equivalent. These findings reinforce the importance of prescribing within the therapeutic dose–response range for ICS in asthma and the need to determine the dose–response relationship for the efficacy of ICS in COPD. Screening for the presence of cataracts could usefully be undertaken in older subjects with asthma and COPD, particularly current or ex–smokers.

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