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See Latest ArticlesInhibition of Protein Kinase C Is not Sufficient to Prevent or Revert Effects of VEGF165 on Tight Junction Protein Claudin-1 and Permeability in Microvascular Retinal Endothelial Cells
Investigative Ophthalmology and Visual Science, 08/05/09
Deissler HL et al. – The authros showed that in iBREC PKC isoforms are not crucially involved in VEGF165–initiated signal transduction affecting permeability and expression of claudin–1. This is in contrast to published results concerning only short–term effects of VEGF165. The authros also confirmed that claudin–1 is a highly relevant component of functional tight junctions in retinal endothelial cells.
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Comparing intravitreal triamcinolone acetonide and bevacizumab injections for the treatment of diabetic macular oedema: a randomized double-blind study
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