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Natural history and outcome of optic pathway gliomas in children
Pediatric Blood & Cancer, 07/23/09
Nicolin G et al. – There was no difference in PFS between chemotherapy versus chemotherapy + debulking or debulking alone. PFS for the NF1 patients who required treatment was similar to that of non–NF1 patients. Mean follow–up time was 9.0 years.The study confirms the complexity of OPGs and that NF1 is a major determinant of the resultant behavior of the tumor.
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