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Multimodal imaging including spectral domain OCT and confocal near infrared reflectance for characterisation of outer retinal pathology in pseudoxanthoma elasticum
Investigative Ophthalmology and Visual Science, 06/25/09
Issa PC et al. - SD-OCT in combination with cSLO imaging using NIR light locates the primary pathology of angioid streaks and peau d orange to Bruch membrane. NIR reflectance imaging may be superior to detect PXE-related fundus lesions at the level of Bruch membrane because blue laser light as used for FAF and FA is markedly absorbed by the pigment epithelium and therefore may only detect alterations if this cell layer is also affected.
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