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Retinal Vessel Abnormalities Are Associated with Elevated Fasting Insulin Levels and Cerebral Atrophy in Nondiabetic Individuals
Ophthalmology, 06/10/09
Tirsi A et al. - These novel findings indicate that insulin resistance short of diabetes and independent of age and hypertension has a negative impact on retinal vessel health. Moreover, impaired retinal vessel health related to brain atrophy also was independent of hypertension and white matter hyperintensities. Given the connections between retinal and cerebral vasculature, this may offer a partial explanation for the presence of cognitive and brain abnormalities among individuals with insulin resistance.
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