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Tumour Necrosis Factor-alpha in Ocular Mucous Membrane Pemphigoid and its effect on Conjunctival Fibroblasts
Investigative Ophthalmology and Visual Science, 06/05/09
Saw VPJ et al. - Increased conjunctival expression of TNF alpha in ocular MMP suggests that systemic TNF alpha antagonists may be effective in controlling severe disease unresponsive to conventional systemic immunosuppression. Residual TNF alpha expression persists in clinically uninflamed disease. TNF alpha appears to have profibrotic effects on human conjunctival fibroblasts.
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