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Current Theories on the Pathogenesis of Infantile Hemangioma
Seminars in Ophthalmology, 05/19/09
Lo K et al. - New investigations have produced sophisticated hypotheses on the origin of these tumors and their behavior. These include suggestions of placental origin, intrinsic defect or somatic endothelial mutation, and extrinsic factors creating a conducive milieu for growth. While no current hypothesis explains all the characteristics of infantile hemangiomas, continued research targeting pathophysiology will ultimately lead to new treatment options.
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