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See Latest ArticlesPI3K/Akt pathway mutations in Retinoblastoma
Investigative Ophthalmology and Visual Science, 05/12/09
Cohen Y et al. - Although the PI3K-AKT pathway is known to be dysregulated in retinoblastoma, the low frequency of oncogenic mutations in the AKT1, PIK3CA and PTEN genes, suggests a different activating mechanism.
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